SCHEMBL8520968

SCHEMBL8520968

O=C(O)N(Cc1ccccc1)[C@@H]1C[C@@H]1F

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.54
AGER Q15109 3/20 0.44
MTNR1A P48039 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CHRM2 P08172 1/20 0.41
CHRM3 P20309 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
OPRM1 P35372 2/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520967 1.00 CTSD (0.54) CTSDAGERMTNR1AMEN1KMT2A
SCHEMBL9054232 0.85 CTSD (0.43) CTSDMEN1KMT2ANPC1RAB9A
SCHEMBL9618427 0.81 HSD11B1 (0.49) CTSDKMT2AKDM4EALDH1A1
SCHEMBL15407540 0.80 CTSD (0.52) CTSDAGERMTNR1AMEN1KMT2A
SCHEMBL1467754 0.80 CTSD (0.56) CTSDAGERMTNR1A
SCHEMBL1976155 0.80 CTSD (0.52) CTSDAGERMTNR1AMEN1KMT2A
SCHEMBL1467752 0.80 CTSD (0.56) CTSDAGERMTNR1A
SCHEMBL1976152 0.80 CTSD (0.52) CTSDAGERMTNR1AMEN1KMT2A
SCHEMBL1976153 0.80 CTSD (0.52) CTSDAGERMTNR1AMEN1KMT2A
SCHEMBL1467750 0.80 CTSD (0.56) CTSDAGERMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743299-B1 Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts BAYER AG (DE) 1999-09-15 EP disclosed