SCHEMBL8520976

SCHEMBL8520976

Nc1nccn1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27692875 0.71 TLR8 (0.40)
SCHEMBL3686973 0.69
SCHEMBL2502618 0.69
SCHEMBL28021236 0.69
SCHEMBL4306554 0.67 ARG1 (0.39)
SCHEMBL22978585 0.67
SCHEMBL5649622 0.67
SCHEMBL5648777 0.67
Water SCHEMBL28845779 0.67
SCHEMBL651400 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331521-B1 COMPOUNDS FOR GROWING HAIR ALLERGAN INC (US) 2013-01-02 EP disclosed
WO-2012065963-A2 NOVEL ANTIVIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2012-05-24 WO disclosed
WO-2011015641-A1 NOVEL VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2011-02-10 WO disclosed
WO-2010130842-A1 THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2010-11-18 WO disclosed
WO-2010019536-A1 THERAPEUTIC COMPOUNDS ALLERGAN, INC. (US) 2010-02-18 WO disclosed