SCHEMBL4306554

SCHEMBL4306554

Nc1nccn1C(=O)n1ccnc1N

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.39
TLR8 Q9NR97 2/20 0.34
NUDT1 P36639 1/20 0.33
PARP1 P09874 1/20 0.32
HPSE Q9Y251 1/20 0.32
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14132348 0.79 ARG1 (0.35) ARG1TLR8
SCHEMBL27348053 0.77 LPO (0.42) ARG1TLR8
SCHEMBL27589887 0.74 FDPS (0.50)
SCHEMBL309967 0.73 FDPS (0.39)
SCHEMBL2698209 0.73 HSP90AA1 (0.42)
SCHEMBL16182089 0.73
SCHEMBL27686570 0.71 FDPS (0.31)
SCHEMBL27831516 0.70 SMN1; SMN2 (0.33) HPSE
SCHEMBL13092480 0.69 TLR8 (0.49) TLR8
SCHEMBL27362838 0.69 ALDH1A1 (0.39) ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002466-A1 PROCESS FOR THE PREPARATION OF CENOBAMATE ANND INTERMEDIATES THEREOF METROCHEM API PVT LTD 2025-01-02 US disclosed
WO-2023152711-A1 PROCESS FOR THE PREPARATION OF CENOBAMATE AND INTERMEDIATES THEREOF METROCHEM API PVT LTD (IN) 2023-08-17 WO disclosed
CN-101784542-B Imidazolone derivatives, preparation method and biological application UNIV RENNES 2014-04-02 CN disclosed
EP-1879873-B1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2013-10-09 EP disclosed
CN-101784542-A Imidazolone derivatives, preparation method and biological application UNIV RENNES 2010-07-21 CN disclosed
US-7598279-B2 Neurotherapeutic azole compounds SK HOLDINGS CO., LTD. (KR) 2009-10-06 US disclosed
US-20060258718-A1 Neurotherapeutic azole compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2006-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258718-A1 Neurotherapeutic azole compounds CHRNA10, CHRNA4, CHRNA3 ARG1 2479/4885TLR8 3032/4885NUDT1 2161/4885
US-20250002466-A1 PROCESS FOR THE PREPARATION OF CENOBAMATE ANND INTERMEDIATES THEREOF TALDO1, AURKB, PGD ARG1 3179/4885TLR8 4737/4885NUDT1 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.