SCHEMBL8521027

SCHEMBL8521027

C=CCc1cc(O)ccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
TTR P02766 1/20 0.41
POLB P06746 2/20 0.40
XDH P47989 1/20 0.38
PTGDR Q13258 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
MEN1 O00255 2/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
CNR1 P21554 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11333301 0.84 HSD17B10 (0.46) HSD17B10GABRA1GABRB2CA12CA1
SCHEMBL4446113 0.81 GABRA1 (0.50) GABRA1GABRB2ESR1ESR2POLB
SCHEMBL71514 0.79 GABRA1 (0.70) GABRA1GABRB2ESR1ESR2POLB
SCHEMBL29837102 0.79 GABRA1 (0.48) GABRA1GABRB2ESR1ESR2POLB
SCHEMBL30893166 0.79 GABRA1 (0.70) GABRA1GABRB2ESR1ESR2POLB
SCHEMBL5931905 0.79 GABRA1 (0.48) GABRA1GABRB2ESR1ESR2POLB
SCHEMBL15066541 0.79 PTGDR (0.50) HSD17B10GABRA1GABRB2POLBPTGDR
SCHEMBL8730439 0.78 GABRA1 (0.47) GABRA1GABRB2ESR1ESR2POLB
SCHEMBL20819282 0.78 CYP3A4 (0.48) HSD17B10GABRA1GABRB2CA1CA2
SCHEMBL8738071 0.76 HSD17B10 (0.56) HSD17B10CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101468951-A Method for preparing 2-chloro-5-(2-chloro-trifluoromethyl phenoxy) benzoyl-L-ethyl lactate UNIV BEIJING CHEMICAL (CN) 2009-07-01 CN claimed
EP-0752418-B1 Method for preparing 4-alkyl-2-hydroxy-3,5-dichlorobenzene sulphonic acids KEMIRA AGRO OY (FI) 1999-09-01 EP claimed
US-5684183-A Method for preparing 4-alkyl-2-hydroxy-3,5-dichlorobenzene sulphonic acids KEMIRA GROWHOW OY (FI) 1997-11-04 US claimed
EP-0752418-A1 Method for preparing 4-alkyl-2-hydroxy-3, 5-dichlorobenzene sulphonic acids KEMIRA AGRO OY (FI) 1997-01-08 EP claimed
US-5136109-A PROCESS FOR PREPARING 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS TAOKA CHEMICAL COMPANY, LTD. (JP) 1992-08-04 US claimed
JP-5078285-A None JP disclosed
JP-5032598-A None JP disclosed
JP-9020748-A None JP disclosed
CN-101591225-A The synthetic method of 5-alkyl resorcinol UNIV EAST CHINA SCIENCE & TECH (CN) 2009-12-02 CN disclosed
CN-101468951-A Method for preparing 2-chloro-5-(2-chloro-trifluoromethyl phenoxy) benzoyl-L-ethyl lactate UNIV BEIJING CHEMICAL (CN) 2009-07-01 CN disclosed
EP-0752418-B1 Method for preparing 4-alkyl-2-hydroxy-3,5-dichlorobenzene sulphonic acids KEMIRA AGRO OY (FI) 1999-09-01 EP disclosed
US-5684183-A Method for preparing 4-alkyl-2-hydroxy-3,5-dichlorobenzene sulphonic acids KEMIRA GROWHOW OY (FI) 1997-11-04 US disclosed
EP-0486606-A1 PROCESS FOR PREPARING 5-CHLOR-2-HYDROXY-4-ALKYL-BENZENE-SULPHONIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-27 EP disclosed
EP-0473464-A1 Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols TAOKA CHEMICAL CO., LTD (JP) 1992-03-04 EP disclosed
EP-0473464-A1 Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols TAOKA CHEMICAL CO., LTD (JP) 1992-03-04 EP disclosed
US-5012015-A Nitrading a trichlorobenzene with mixed acid, hydrolysis DAIEI CHEMICAL CO., LTD. (JP) 1991-04-30 US disclosed
WO-1991002717-A1 PROCESS FOR PREPARING 5-CHLOR-2-HYDROXY-4-ALKYL-BENZENE-SULPHONIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-07 WO disclosed
EP-0175151-B1 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1989-01-18 EP disclosed
US-4670608-A CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US disclosed
EP-0175151-A1 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation BAYER AG (DE) 1986-03-26 EP disclosed