SCHEMBL15066541

SCHEMBL15066541

C=CCc1cc(Cl)ccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.50
TP53 P04637 2/20 0.42
MAPT P10636 4/20 0.42
CYP3A4 P08684 4/20 0.42
HPGD P15428 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 5/20 0.40
LMNA P02545 3/20 0.40
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
THRB P10828 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
IDO1 P14902 2/20 0.39
SLC22A1 O15245 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249746 0.83 IDO1 (0.54) PTGDRPTGDR2TP53MAPTCYP3A4
SCHEMBL30956678 0.83 IDO1 (0.54) PTGDRPTGDR2TP53MAPTCYP3A4
SCHEMBL20819282 0.81 CYP3A4 (0.48) PTGDRPTGDR2MAPTCYP3A4HPGD
Bromide SCHEMBL28225209 0.81 IDO1 (0.52) PTGDRPTGDR2TP53MAPTCYP3A4
SCHEMBL29135543 0.79 PTGDR (0.47) PTGDRPTGDR2MAPTCYP3A4HPGD
SCHEMBL21546530 0.79 PTGDR (0.47) PTGDRPTGDR2TP53MAPTCYP3A4
SCHEMBL2490536 0.79 GABRA1 (0.66) PTGDRPTGDR2MAPTCYP3A4HPGD
SCHEMBL28255167 0.79 PTGDR (0.47) PTGDRPTGDR2MAPTCYP3A4HPGD
SCHEMBL22642139 0.79 HPGD (0.41) PTGDRPTGDR2TP53MAPTHPGD
SCHEMBL8521027 0.79 HSD17B10 (0.46) PTGDRPTGDR2MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797881-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed