Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26920424 | 0.83 | PTGER4 (0.61) | MAPTALDH1A1PTGER4THRBHPGD | |
| SCHEMBL8720435 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1LMNATHRBHPGD | |
| SCHEMBL28226632 | 0.73 | ALDH1A1 (0.45) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL622250 | 0.72 | MAPT (0.47) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9262055 | 0.72 | ALDH1A1 (0.58) | MAPTALDH1A1LMNAGRIN2DGRIN3B | |
| SCHEMBL1653792 | 0.72 | GPR35 (0.49) | MAPTALDH1A1LMNAKAT2BL3MBTL1 | |
| SCHEMBL9370714 | 0.72 | GPR35 (0.49) | MAPTALDH1A1LMNAKAT2BMEN1 | |
| SCHEMBL7779743 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL8609981 | 0.71 | HSP90AA1 (0.49) | MAPTALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL29467493 | 0.71 | PTGER4 (0.54) | MAPTALDH1A1LMNAPTGER4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977107-A | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones and the use thereof as glycine receptor antagonists | COCENSYS, INC. (US) | 1999-11-02 | — | — | US | disclosed |