Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA4 | P22748 | 3/20 | 0.31 |
| ▸ | CA5A | P35218 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521393 | 1.00 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8521180 | 1.00 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8520913 | 1.00 | PRKCA (0.32) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8520278 | 0.96 | PRKCA (0.33) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL3482282 | 0.77 | PRKCA (0.37) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL29974888 | 0.77 | PRKCA (0.36) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8520054 | 0.77 | ABCB1 (0.31) | — | |
| SCHEMBL8520785 | 0.77 | ABCB1 (0.31) | — | |
| SCHEMBL4374202 | 0.76 | PRKCA (0.34) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL9986360 | 0.76 | PRKCA (0.34) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888777-A | Process for the complete removal of protective groups on nucleoside diphosphate and triphosphate sugars with acetylesterase | NOVARTIS AG (CH) | 1999-03-30 | — | — | US | disclosed |
| EP-0801684-A1 | PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS | Novartis AG (CH) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996024683-A1 | PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS | NOVARTIS AG (CH) | 1996-08-15 | — | — | WO | disclosed |