Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520785 | 1.00 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL8520278 | 0.78 | PRKCA (0.33) | — | |
| SCHEMBL8521371 | 0.77 | PRKCA (0.32) | — | |
| SCHEMBL8521393 | 0.77 | PRKCA (0.32) | — | |
| SCHEMBL8521180 | 0.77 | PRKCA (0.32) | — | |
| SCHEMBL8520913 | 0.77 | PRKCA (0.32) | — | |
| SCHEMBL8520288 | 0.65 | — | — | |
| Phosphoric Acid SCHEMBL8773417 | 0.64 | OGA (0.42) | — | |
| SCHEMBL34470432 | 0.63 | CA9 (0.39) | — | |
| SCHEMBL17285152 | 0.63 | CA9 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888777-A | Process for the complete removal of protective groups on nucleoside diphosphate and triphosphate sugars with acetylesterase | NOVARTIS AG (CH) | 1999-03-30 | — | — | US | disclosed |
| EP-0801684-A1 | PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS | Novartis AG (CH) | 1997-10-22 | — | — | EP | disclosed |
| WO-1996024683-A1 | PROCESS FOR THE COMPLETE REMOVAL OF PROTECTIVE GROUPS ON NUCLEOSIDE DIPHOSPHATE AND TRIPHOSPHATE SUGARS | NOVARTIS AG (CH) | 1996-08-15 | — | — | WO | disclosed |