Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20258489 | 0.86 | HTR3E (0.42) | MAPK1TDP1TP53CYP3A4TSHR | |
| SCHEMBL7567112 | 0.83 | TSHR (0.44) | MAPK1TDP1TP53CYP3A4TSHR | |
| SCHEMBL16906397 | 0.80 | MAPT (0.52) | MAPK1TDP1TP53CYP3A4TSHR | |
| SCHEMBL16906398 | 0.80 | MAPT (0.52) | MAPK1TDP1TP53CYP3A4TSHR | |
| SCHEMBL23954017 | 0.78 | IDO1 (0.54) | TDP1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18084255 | 0.78 | FFAR4 (0.40) | MAPK1TDP1TP53CYP3A4TSHR | |
| SCHEMBL9657592 | 0.77 | MEN1 (0.52) | MAPK1TDP1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL9657595 | 0.77 | MEN1 (0.52) | MAPK1TDP1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL5982583 | 0.77 | ALDH1A1 (0.50) | MAPK1TDP1TP53CYP3A4TSHR | |
| SCHEMBL5983562 | 0.77 | ALDH1A1 (0.50) | MAPK1TDP1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856430-A | Process and materials for inducing pre-tilt in liquid crystals and liquid crystal displays | ALLIANT TECHSYSTEMS INC. (US) | 1999-01-05 | — | — | US | disclosed |