Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427147 | 1.00 | KMT2A (0.48) | KMT2ASMN1; SMN2NPSR1TSHRKIF11 | |
| SCHEMBL10354426 | 0.81 | CYP2A6 (0.34) | KMT2A | |
| SCHEMBL10989568 | 0.81 | CYP2A6 (0.34) | KMT2A | |
| SCHEMBL8778877 | 0.78 | CYP2A6 (0.35) | KMT2ATSHR | |
| SCHEMBL116043 | 0.78 | ALOX5AP (0.39) | TSHRKIF11RAB9AKDM4E | |
| SCHEMBL16472121 | 0.78 | ALOX5AP (0.39) | TSHRKIF11RAB9AKDM4E | |
| SCHEMBL11200036 | 0.78 | CYP2A6 (0.36) | KMT2A | |
| SCHEMBL29595709 | 0.77 | NPSR1 (0.53) | KMT2ASMN1; SMN2NPSR1TSHRKIF11 | |
| SCHEMBL811160 | 0.77 | NPSR1 (0.53) | KMT2ASMN1; SMN2NPSR1TSHRKIF11 | |
| SCHEMBL10691786 | 0.77 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2NPSR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 852 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106499-A1 | OREXIN RECEPTOR ANTAGONISTS: 2-AZABICYCLIC COMPOUNDS | BIAL - PORTELA & CA., S.A. (PT) | 2026-05-21 | — | — | WO | claimed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| CN-114361590-B | Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery | 松山湖材料实验室 | 2023-07-25 | — | — | CN | claimed |
| US-20220372332-A1 | With-In Die Non-Uniformities (WID-NU) In Planarization | VERSUM MATERIALS US, LLC (US) | 2022-11-24 | — | — | US | claimed |
| CN-109678791-B | 1- (2, 4-difluorophenyl) -2, 2-difluoro-2- (5-substituted pyridine-2-yl) ethanone and preparation method thereof | 美国陶氏益农公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114361590-A | Lithium ion battery electrolyte additive, electrolyte and lithium ion battery | 松山湖材料实验室 | 2022-04-15 | — | — | CN | claimed |
| EP-3119756-B1 | 2-(2,4-DIFLUOROPHENYL)-1,1-DIFLUORO-1-(5-SUBSTITUTED-PYRIDIN-2-YL)-3-(1H-TETRAZOL-1-YL)PROPAN-2-OLS AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2021-04-21 | — | — | EP | claimed |
| WO-2021061591-A1 | WITH-IN DIE NON-UNIFORMITIES (WID-NU) IN PLANARIZATION | VERSUM MATERIALS US, LLC (US) | 2021-04-01 | — | — | WO | claimed |
| CN-112321495-A | Preparation method of 2-fluoro-5- (trifluoromethyl) pyridine | 南京麦瑞米生物技术有限公司 | 2021-02-05 | — | — | CN | claimed |
| EP-0183228-A2 | Chlorine exchange for fluorine in 2-fluoro-pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1986-06-04 | — | — | EP | claimed |
| US-4567274-A | TRICHLOROMETHYL OR DICHLORFLUOROMETHLPICOLINE | THE DOW CHEMICAL COMPANY (US) | 1986-01-28 | — | — | US | claimed |
| US-4546192-A | Chlorine exchange for fluorine in ring-fluorinated pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | claimed |
| EP-0063872-B1 | PROCESS FOR THE PREPARATION OF FLUOROMETHYL PYRIDINES AND CERTAIN NOVEL PRODUCTS OBTAINED THEREFROM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-17 | — | — | EP | claimed |
| US-4493932-A | Chlorine exchange for fluorine in 2-fluoro-pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-01-15 | — | — | US | claimed |
| US-4490534-A | CHLORINATION IN VAPOR PHASE, PRESENCE OF CATALYST | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-12-25 | — | — | US | claimed |
| EP-0107866-A2 | Trihalomethylpyridine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-09 | — | — | EP | claimed |
| EP-0078410-A2 | Process for producing 3-chloro-5-trifluoromethylpyridines | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-05-11 | — | — | EP | claimed |
| EP-0063872-A1 | Process for the preparation of fluoromethyl pyridines and certain novel products obtained therefrom | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-03 | — | — | EP | claimed |
| US-4184041-A | 2-Substituted-5-trifluoromethylpyridine compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1980-01-15 | — | — | US | claimed |