SCHEMBL811160

SCHEMBL811160

FC(F)(F)c1ccc(-c2ccc(C(F)(F)F)cn2)nc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.53
KDM4E B2RXH2 2/20 0.51
KMT2A Q03164 2/20 0.50
KIF11 P52732 2/20 0.50
CASP3 P42574 2/20 0.44
KDM1A O60341 1/20 0.43
MAOB P27338 1/20 0.43
TRPV3 Q8NET8 1/20 0.42
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
PTGS1 P23219 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29595709 1.00 NPSR1 (0.53) NPSR1KDM4EKMT2AKIF11CASP3
SCHEMBL25012750 0.89 NPSR1 (0.46) NPSR1KDM4EKMT2AKIF11CASP3
SCHEMBL27344645 0.88 KIF11 (0.63) NPSR1KDM4EKMT2AKIF11CASP3
SCHEMBL24689583 0.87 CCR1 (0.64) NPSR1KDM4EKMT2AKIF11CASP3
SCHEMBL13830687 0.86 NPSR1 (0.50) NPSR1KDM4EKMT2AKIF11CASP3
SCHEMBL28530523 0.86 KIF11 (0.61) NPSR1KDM4EKMT2AKIF11KDM1A
SCHEMBL29690424 0.86 KIF11 (0.61) NPSR1KDM4EKMT2AKIF11KDM1A
SCHEMBL4342508 0.84 KIF11 (0.59) NPSR1KDM4EKMT2AKIF11KDM1A
SCHEMBL30238069 0.84 NPSR1 (0.43) NPSR1KDM4EKMT2AKIF11CASP3
SCHEMBL3180184 0.83 CYP11B1 (0.55) NPSR1KDM4EKMT2AKIF11KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
US-20220259240-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2022-08-18 US claimed
EP-4013764-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES Johnson Matthey Public Limited Company (GB) 2022-06-22 EP claimed
WO-2021032952-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2021-02-25 WO claimed
US-20050233233-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes RADU NORA S 2005-10-20 US claimed
EP-1406909-A1 LUMINESCENT LANTHANIDE COMPLEXES WITH IMINE LIGANDS AND DEVICES MADE WITH SUCH COMPLEXES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-04-14 EP claimed
US-20030129450-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes LG CHEM, LTD. (KR) 2003-07-10 US claimed
WO-2003008424-A1 LUMINESCENT LANTHANIDE COMPLEXES WITH IMINE LIGANDS AND DEVICES MADE WITH SUCH COMPLEXES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-01-30 WO claimed
US-20260028351-A1 KCC2 POTENTIATORS AND USES THEREOF AXONIS THERAPEUTICS, INC. 2026-01-29 US disclosed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO disclosed
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 US disclosed
US-20240002927-A1 METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION BLUECAT IP LIMITED (GB) 2024-01-04 US disclosed
EP-1214596-A1 GLUCOSE SENSING MOLECULES HAVING SELECTED FLUORESCENT PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-06-19 EP disclosed
US-20020043651-A1 Fluorescent lifetime assays for non-invasive quantification of analytes such as glucose ENERGY, U.S. DEPARTMENT OF 2002-04-18 US disclosed
US-20020010279-A1 Saccharide sensing molecules having enhanced fluorescent properties LAWRENCE LIVERMORE NATIONAL SECURITY LLC 2002-01-24 US disclosed
WO-2001075450-A2 FLUORESCENT LIFETIME ASSAYS FOR NON-INVASIVE QUANTIFICATION OF ANALYTES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-10-11 WO disclosed
WO-2001074968-A2 SACCHARIDE SENSING MOLECULES HAVING ENHANCED FLUORESCENT PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-10-11 WO disclosed
WO-2001020334-A1 GLUCOSE SENSING MOLECULES HAVING SELECTED FLUORESCENT PROPERTIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233233-A1 Luminescent lanthanide complexes with imine ligands and devices made with such complexes SSB, LARP7, LIG3 NPSR1 2134/4885KDM4E 2479/4885KMT2A 3459/4885
US-20260028351-A1 KCC2 POTENTIATORS AND USES THEREOF GRIN2C, HCN1, KCNC1 NPSR1 503/4885KDM4E 3650/4885KMT2A 2979/4885
US-20020010279-A1 Saccharide sensing molecules having enhanced fluorescent properties SLC2A1, SLC2A9, SLC2A2 NPSR1 2303/4885KDM4E 3240/4885KMT2A 4458/4885
US-20220259240-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES RUVBL1, RUVBL2, RPP30 NPSR1 2631/4885KDM4E 2618/4885KMT2A 4330/4885
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 NPSR1 720/4885KDM4E 4590/4885KMT2A 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.