SCHEMBL8522007

SCHEMBL8522007

COc1cc2c(cc1OC)C(=O)C(O)C2

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8938844 0.80 ACHE (1.00) ACHE
SCHEMBL12043670 0.79 ACHE (0.63) ACHE
SCHEMBL700378 0.79 ACHE (0.67) ACHE
SCHEMBL29369832 0.79 ACHE (0.67) ACHE
SCHEMBL9741674 0.79 ACHE (0.67) ACHE
SCHEMBL29752706 0.79 ACHE (0.67) ACHE
SCHEMBL4859012 0.78 ACHE (0.61) ACHE
SCHEMBL10427199 0.77 ACHE (0.65) ACHE
SCHEMBL3085512 0.77 ACHE (0.59) ACHE
SCHEMBL3085511 0.77 ACHE (0.59) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372507-B Novel method for preparing chiral alpha-hydroxy-beta-dicarbonyl compound by photocatalytic asymmetric oxidation 大连理工大学 2022-04-15 CN disclosed
CN-110372506-B Novel method for realizing visible light catalytic asymmetric oxidation by utilizing microreactor 大连理工大学 2022-04-15 CN disclosed
EP-0712387-B1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS UPJOHN CO (US) 1999-12-08 EP disclosed
US-5708018-A 2-aminoindans as selective dopamine D3 ligands PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 US disclosed
EP-0712387-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS PHARMACIA & UPJOHN COMPANY (US) 1996-05-22 EP disclosed
WO-1995004713-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS THE UPJOHN COMPANY (US) 1995-02-16 WO disclosed