Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961833 | 0.92 | FAAH (0.41) | KCNH2MCHR1FAAHCHRNB2SPHK2 | |
| SCHEMBL6963235 | 0.90 | FAAH (0.40) | KCNH2MCHR1FAAHCHRNB2CHRNA5 | |
| SCHEMBL6963231 | 0.90 | FAAH (0.40) | KCNH2MCHR1FAAHCHRNB2CHRNA5 | |
| SCHEMBL6967496 | 0.89 | HPGD (0.47) | — | |
| SCHEMBL6969419 | 0.89 | HPGD (0.47) | — | |
| SCHEMBL6970975 | 0.89 | HPGD (0.47) | — | |
| SCHEMBL6976242 | 0.89 | FAAH (0.46) | KCNH2MCHR1FAAHCHRNB2CHRNA5 | |
| SCHEMBL6976244 | 0.89 | FAAH (0.46) | KCNH2MCHR1FAAHCHRNB2CHRNA5 | |
| Hydrochloric Acid SCHEMBL6958761 | 0.88 | HPGD (0.47) | — | |
| Maleic Acid SCHEMBL6974160 | 0.85 | HPGD (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894089-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997041121-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |