Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522230 | 0.92 | KCNH2 (0.39) | FAAHKCNH2MCHR1SPHK1SPHK2 | |
| SCHEMBL6958917 | 0.88 | CNR1 (0.43) | MAOAMAOBPOLB | |
| SCHEMBL6958913 | 0.88 | CNR1 (0.43) | MAOAMAOBPOLB | |
| SCHEMBL8523688 | 0.88 | FAAH (0.57) | FAAHKCNH2MCHR1SPHK1SPHK2 | |
| SCHEMBL6963235 | 0.85 | FAAH (0.40) | FAAHMAOAMAOBKCNH2MCHR1 | |
| SCHEMBL6963231 | 0.85 | FAAH (0.40) | FAAHMAOAMAOBKCNH2MCHR1 | |
| SCHEMBL6976244 | 0.84 | FAAH (0.46) | FAAHKCNH2MCHR1SPHK1CHRNB2 | |
| SCHEMBL6976242 | 0.84 | FAAH (0.46) | FAAHKCNH2MCHR1SPHK1CHRNB2 | |
| SCHEMBL6967496 | 0.82 | HPGD (0.47) | MAOAMAOBPOLB | |
| SCHEMBL6969419 | 0.82 | HPGD (0.47) | MAOAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894089-B9 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2003-04-02 | — | — | EP | disclosed |
| EP-0894089-B1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2002-10-23 | — | — | EP | disclosed |
| US-5889032-A | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-30 | — | — | US | disclosed |