Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.65 |
| ▸ | CDK2 | P24941 | 3/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.65 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.65 |
| ▸ | CDK4 | P11802 | 2/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.65 |
| ▸ | CCND1 | P24385 | 2/20 | 0.65 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232107 | 1.00 | CDK1 (0.65) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL7232100 | 1.00 | CDK1 (0.65) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL7229755 | 0.92 | ADORA3 (0.70) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL7229760 | 0.92 | ADORA3 (0.70) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL5138486 | 0.85 | ADORA3 (0.59) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL5138159 | 0.84 | ADORA3 (0.58) | ADORA3ADORA2AADORA1ADORA2BHTR2C | |
| SCHEMBL5088082 | 0.84 | ADORA2A (0.58) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL5088084 | 0.84 | ADORA2A (0.58) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL5088983 | 0.84 | ADORA2A (0.68) | CDK1CCNE1CDK2CCNB2CCNE2 | |
| SCHEMBL7525816 | 0.84 | ADORA2A (0.68) | CDK1CCNE1CDK2CCNB2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028319-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-07-02 | — | — | WO | disclosed |