Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 3/20 | 0.56 |
| ▸ | CDK4 | P11802 | 3/20 | 0.56 |
| ▸ | CCND1 | P24385 | 3/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.56 |
| ▸ | CDK2 | P24941 | 3/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654876 | 0.84 | CCNE2 (0.58) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8074992 | 0.83 | PRKCA (0.63) | CCNE2CDK4CCND1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL8065191 | 0.83 | PRKCA (0.62) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8075731 | 0.77 | PIM1 (0.70) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8578928 | 0.77 | CCNE2 (0.59) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8167903 | 0.77 | CCNE2 (0.72) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8073164 | 0.76 | PIM1 (0.50) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30319849 | 0.75 | CCNE2 (1.00) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5686048 | 0.75 | CCNE2 (1.00) | CCNE2CDK4CCND1CCNE1CDK2 | |
| Hydrochloric Acid SCHEMBL8074734 | 0.74 | PRKCB (0.61) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | claimed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | claimed |