Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854436 | 0.81 | OPRM1 (0.40) | FKBP1AGAANPC1MAPK1RAB9A | |
| SCHEMBL16714152 | 0.75 | OPRM1 (0.38) | FKBP1AGAANPC1MAPK1RAB9A | |
| SCHEMBL855707 | 0.73 | OGFRL1 (0.39) | FKBP1AGAANPC1MAPK1RAB9A | |
| SCHEMBL551433 | 0.73 | DDB1 (0.48) | FKBP1ADDB1CRBN | |
| SCHEMBL550752 | 0.72 | OPRM1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL25554839 | 0.71 | TSHR (0.49) | — | |
| SCHEMBL13221719 | 0.71 | OGFRL1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL551499 | 0.68 | KDM4E (0.44) | FKBP1AGAAKDM4EMAPT | |
| SCHEMBL3724255 | 0.67 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL550300 | 0.66 | CTSL (0.42) | FKBP1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433937-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |