SCHEMBL852266

SCHEMBL852266

CC(C)(C)c1cc(OCO)cc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.37
CD69 Q07108 2/20 0.37
ELANE P08246 1/20 0.37
CYP2C19 P33261 1/20 0.35
HMGCR P04035 2/20 0.35
HTR1D P28221 2/20 0.34
HTR1B P28222 1/20 0.34
RXRA P19793 3/20 0.34
RXRB P28702 3/20 0.34
RXRG P48443 3/20 0.34
CNR1 P21554 4/20 0.33
CNR2 P34972 4/20 0.33
POLB P06746 1/20 0.33
SOD1 P00441 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2678698 0.83 SMN1; SMN2 (0.49) GABRA1GABRB2SMN1; SMN2RXRARXRB
SCHEMBL7879116 0.81 GABRA1 (0.41) GABRA1GABRB2SMN1; SMN2CNR1CNR2
SCHEMBL27908502 0.79 GABRA1 (0.40) GABRA1GABRB2SMN1; SMN2CD69ELANE
SCHEMBL485746 0.79 SOD1 (0.53) CYP2C19POLBSOD1
SCHEMBL25468623 0.79 NQO1 (0.46) GABRA1GABRB2SMN1; SMN2CD69ELANE
SCHEMBL2097371 0.77 SOD1 (0.47) RXRARXRBRXRGSOD1
SCHEMBL1271546 0.77 SMN1; SMN2 (0.60) SMN1; SMN2RXRARXRBPOLB
SCHEMBL10197366 0.75 SMN1; SMN2 (0.49) GABRA1GABRB2SMN1; SMN2CD69ELANE
SCHEMBL9503312 0.75 SMN1; SMN2 (0.68) SMN1; SMN2CD69ELANECYP2C19RXRA
SCHEMBL278323 0.74 NQO1 (0.46) GABRA1GABRB2SMN1; SMN2ELANEHMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3943239-A PYRETHROID SUMITOMO CHEMICAL CO., LTD. (JA) 1976-03-09 US claimed
EP-1655321-B1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME ZEON CORP (JP) 2012-11-21 EP disclosed
EP-1655319-B1 POLYMERIZABLE COMPOSITION AND FORMED BODY THEREOF ZEON CORP (JP) 2012-03-28 EP disclosed
US-7803870-B2 Polymerizable composition and molded product thereof ZEON CORPORATION (JP) 2010-09-28 US disclosed
US-7771834-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2010-08-10 US disclosed
US-7666966-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2010-02-23 US disclosed
US-20090270552-A1 POLYMERIZABLE COMPOSITION AND MOLDED PRODUCT THEREOF SUGAWARA TOMOO 2009-10-29 US disclosed
US-7579404-B2 Polymerizable composition and molded product thereof ZEON CORPORATION (JP) 2009-08-25 US disclosed
US-20090036614-A1 METHOD OF MANUFACTURING THERMOPLASTIC RESIN, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIAL ZEON CORPORATION 2009-02-05 US disclosed
US-7476716-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2009-01-13 US disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
US-20060211834-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2006-09-21 US disclosed
US-20060205901-A1 Crosslinkable resin composition and resin formed body produced therefrom ZEON CORPORATION (JP) 2006-09-14 US disclosed
EP-1655343-A1 CROSSLINKABLE RESIN COMPOSITION AND RESIN FORMED BODY PRODUCED THEREFROM Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1655319-A1 POLYMERIZABLE COMPOSITION AND FORMED BODY THEREOF Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed
US-20040204521-A1 Additive functionalized organophilic nano-scaled fillers CIBA SPECIALTY CHEMICALS CORP. 2004-10-14 US disclosed
US-6365651-B1 Synergistic stabilizer mixture CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
US-6359148-B1 FOR POLYMER, LUBRICANTS; HEAT, OXIDATION RESISTANCE, PHOTOSTABILITY NESVADBA PETER (CH) 2002-03-19 US disclosed