Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.59 |
| ▸ | ACE | P12821 | 12/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027260 | 1.00 | MME (0.59) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8027091 | 0.94 | MME (0.60) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8027670 | 0.90 | MME (0.73) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8452763 | 0.90 | MME (0.73) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL8027674 | 0.90 | MME (0.73) | MMEACEITGA4ITGB7ITGB1 | |
| SCHEMBL9007741 | 0.88 | MME (0.64) | MMEACEPPARGPPARA | |
| SCHEMBL8447804 | 0.88 | MME (0.64) | MMEACEPPARGPPARA | |
| SCHEMBL8027420 | 0.87 | MME (0.77) | MMEACEPPARGPPARA | |
| SCHEMBL8028033 | 0.87 | MME (0.64) | MMEACE | |
| SCHEMBL8028028 | 0.87 | MME (0.64) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |