Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 9/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180856 | 0.83 | ICAM1 (0.42) | ICAM1HDAC6MEN1USP2CYP1A2 | |
| SCHEMBL6752117 | 0.83 | ICAM1 (0.45) | ICAM1MEN1DRD2KMT2AKDM4E | |
| SCHEMBL8522768 | 0.79 | ICAM1 (0.36) | ICAM1HDAC6CHRM2HTR1ACHRM1 | |
| SCHEMBL6747555 | 0.74 | HDAC6 (0.44) | ICAM1HDAC6MEN1HRH1KMT2A | |
| SCHEMBL7144340 | 0.74 | HDAC6 (0.42) | HDAC6MEN1CYP1A2CHRM2HTR1A | |
| SCHEMBL8315505 | 0.73 | HDAC6 (0.45) | HDAC6MEN1CYP1A2CHRM2HTR1A | |
| SCHEMBL6745150 | 0.73 | HDAC6 (0.44) | HDAC6MEN1CYP1A2CHRM2HTR1A | |
| SCHEMBL6747463 | 0.73 | HDAC6 (0.44) | HDAC6MEN1USP2CYP1A2ADRB2 | |
| SCHEMBL6750179 | 0.72 | HDAC6 (0.46) | HDAC6MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6747320 | 0.70 | HDAC6 (0.57) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |