Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 8/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752121 | 0.86 | ICAM1 (0.35) | ICAM1FAAHPOLBMEN1KMT2A | |
| SCHEMBL7149885 | 0.85 | ICAM1 (0.53) | ICAM1FAAHPOLBMEN1KMT2A | |
| SCHEMBL8522771 | 0.83 | ICAM1 (0.43) | ICAM1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7149891 | 0.79 | ALDH1A1 (0.35) | ICAM1FAAHPOLBMEN1KMT2A | |
| SCHEMBL6751888 | 0.69 | ICAM1 (0.43) | ICAM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6751892 | 0.69 | ICAM1 (0.43) | ICAM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6746486 | 0.67 | ICAM1 (0.42) | ICAM1FAAH | |
| SCHEMBL7173360 | 0.67 | ICAM1 (0.45) | ICAM1MEN1KMT2ADRD2 | |
| SCHEMBL7180856 | 0.67 | ICAM1 (0.42) | ICAM1FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL6749892 | 0.67 | ALDH1A1 (0.36) | ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | ICAM1 412/4885FAAH 604/4885POLB 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.