Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711960 | 0.81 | MAPT (0.56) | EGFRSRCALOX15MTNR1AMTNR1B | |
| SCHEMBL7114553 | 0.80 | KDM4E (0.48) | EGFRSRCMEN1KMT2ATSHR | |
| SCHEMBL7114556 | 0.80 | KDM4E (0.48) | EGFRSRCMEN1KMT2ATSHR | |
| SCHEMBL8097842 | 0.80 | KDM4E (0.48) | EGFRSRCMEN1KMT2ATSHR | |
| SCHEMBL29138493 | 0.79 | MTNR1A (0.54) | EGFRSRCALOX15MTNR1AMTNR1B | |
| SCHEMBL29138501 | 0.78 | MTNR1A (0.50) | EGFRSRCALOX15MTNR1AMTNR1B | |
| SCHEMBL29138488 | 0.78 | EGFR (0.47) | EGFRSRCALOX15MTNR1AMTNR1B | |
| SCHEMBL29138503 | 0.78 | MTNR1A (0.50) | EGFRSRCALOX15MTNR1AMTNR1B | |
| SCHEMBL29138511 | 0.78 | MTNR1A (0.52) | EGFRSRCALOX15MTNR1AMTNR1B | |
| SCHEMBL22189187 | 0.77 | EGFR (0.52) | EGFRSRCALOX15MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955421-A | OXIDATION RESISTANCE; ENHANCING GROWTH HORMONE RELEASE | MEDIOLANUM PHARMACEUTICALS LIMITED (IE) | 1999-09-21 | — | — | US | disclosed |
| US-5872100-A | Peptides containing D-2-Alkyl-Tryptophan | ARDANA BIOSCIENCE LIMITED (GB) | 1999-02-16 | — | — | US | disclosed |
| US-5668254-A | BIOACTIVE, OXIDATION RESISTANCE | Deghenghi, Romano (CH) | 1997-09-16 | — | — | US | disclosed |
| US-5646301-A | INCORPORATION INTO PEPTIDES | Deghenghi, Romano (CH) | 1997-07-08 | — | — | US | disclosed |
| US-5635379-A | PREPARED FROM N-ALPHA-ACETYL-2-ALKYL TRYPTOPHAN RACEMIC MIXTURE | Deghenghi, Romano (CH) | 1997-06-03 | — | — | US | disclosed |