Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138511 | 0.80 | MTNR1A (0.52) | EGFRSRCCYP2C19MEN1CYP1A2 | |
| SCHEMBL29138493 | 0.80 | MTNR1A (0.54) | EGFRSRCCYP2C19MEN1CYP1A2 | |
| SCHEMBL29138503 | 0.79 | MTNR1A (0.50) | EGFRSRCCYP2C19MEN1CYP1A2 | |
| SCHEMBL29138501 | 0.79 | MTNR1A (0.50) | EGFRSRCCYP2C19MEN1CYP1A2 | |
| SCHEMBL8522940 | 0.78 | EGFR (0.50) | EGFRSRCCYP2C19MEN1CYP1A2 | |
| SCHEMBL9303976 | 0.78 | MTNR1A (0.69) | CYP2C19MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29138484 | 0.78 | MTNR1A (0.52) | EGFRSRCCYP2C19MEN1CYP1A2 | |
| SCHEMBL8711960 | 0.77 | MAPT (0.56) | EGFRSRCMEN1CYP3A4TSHR | |
| SCHEMBL7362447 | 0.77 | CYP2C19 (0.60) | CYP2C19HPGDALOX15MAPTALDH1A1 | |
| SCHEMBL7362451 | 0.77 | CYP2C19 (0.60) | CYP2C19HPGDALOX15MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069645-A | Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide | 兰州大学 | 2023-11-17 | — | — | CN | disclosed |