SCHEMBL8522972

SCHEMBL8522972

C=CCN1CCOC(=O)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
DRD3 P35462 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
DRD2 P14416 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7289691 0.78
SCHEMBL1708734 0.74
SCHEMBL24864597 0.71 DAO (0.32)
SCHEMBL3042153 0.71 KDM4E (0.45) CYP3A4LMNAGAAKDM4EMEN1
SCHEMBL4246548 0.71 ALDH1A1 (0.37) LMNAGAADRD3KDM4EMEN1
SCHEMBL2003555 0.70 CYP3A4 (0.33) CYP3A4KDM4EHDAC3HDAC4HDAC1
SCHEMBL11731726 0.70 ALDH1A1 (0.39) CYP3A4LMNAGAAKDM4EKMT2A
SCHEMBL2458108 0.69
SCHEMBL1578946 0.69
SCHEMBL3035191 0.69 HSD17B10 (0.52) LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630959-B1 Fuel composition TEXACO DEVELOPMENT CORP (US) 1998-06-17 EP claimed
EP-0554007-B1 Catalytic synthesis of alkyl morpholinones HUNTSMAN CORP (US) 1998-05-27 EP claimed
EP-0574203-B1 Fuel additives TEXACO DEVELOPMENT CORP (US) 1997-11-05 EP claimed
EP-0596602-B1 Diesel fuel additive providing clean up detergency of fuel injectors TEXACO DEVELOPMENT CORP (US) 1997-04-16 EP claimed
WO-1997006225-A1 MOTOR FUEL DETERGENT ADDITIVES TEXACO DEVELOPMENT CORPORATION (US) 1997-02-20 WO claimed
US-5567211-A ANTIDEPOSIT AGENT COMPRISING AN AMIDO ALKANOLAMINE REACTION PRODUCT OF 4-ALKYL-2-MORPHOLINONE AND AN ALKYLPHENOXYPOLYOXYALKYLENE AMINE AND A POLYISOBUTYLENE AMINE TEXACO INC. (US) 1996-10-22 US claimed
US-5558684-A REACTION PRODUCT OF 4-ALKYL-2-MORPHOLINONE AND ALKYLPHENOXYPOLYOXYALKYLENE AMINE TO PREVENT HAZE TEXACO INC. (US) 1996-09-24 US claimed
US-5383942-A Reaction of 4-alkyl-2-morpholinone and oxypolyalkylene amine to form amido alkanolamine as antideposit agents in fuel combustion TEXACO INC. (US) 1995-01-24 US claimed
EP-0630959-A1 Fuel composition TEXACO DEVELOPMENT CORPORATION (US) 1994-12-28 EP claimed
US-5332407-A Reaction product of N-alkyl-2-morpholinone and ethylene oxide-alkylphenol adduct or polymer TEXACO INC. (US) 1994-07-26 US claimed
US-5286264-A Antideposit agents for intake valves and combustion chambers of internal combustion engines comprising a 4-alkylmorpholin-2-one-modified polyether; a polyalkenyl succinimide and a polyalphaolefin TEXACO INC. (US) 1994-02-15 US claimed
EP-0574203-A1 Fuel additive TEXACO DEVELOPMENT CORPORATION (US) 1993-12-15 EP claimed
US-5234478-A Amido alkanolamine obtained by reacting 4-alkyl-2-morpholine with alkylphenoxypolyoxyalkylene amine TEXACO INC. (US) 1993-08-10 US claimed
EP-0554007-A1 Catalytic synthesis of alkyl morpholinones Huntsman Corporation (US) 1993-08-04 EP claimed
US-5203879-A An amido alkanolamine additive; amidating a polyoxyalkylene amine with a 4-alkyl-2-morpholinone TEXACO INC. (US) 1993-04-20 US claimed
US-5136035-A Catalytic synthesis of alkyl morpholinones TEXACO CHEMICAL COMPANY (US) 1992-08-04 US claimed
US-5066804-A Preparation of alkyl morpholinones TEXACO CHEMICAL COMPANY (US) 1991-11-19 US claimed
JP-6212175-A None JP disclosed
US-4130711-A DEHYDROGENATION OF A N-HYDROXYALKYL N-AMIDOALKYL AMINE, REDUCED COPPER CATALYST THE DOW CHEMICAL COMPANY (US) 1978-12-19 US disclosed
US-4082748-A CATALYTIC DEHYDROCYCLIZATION THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed