Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547809 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL6550542 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL6549162 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL6550074 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL9489161 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL9098888 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL11043183 | 0.98 | LTB4R (0.57) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL6669407 | 0.94 | THRA (0.55) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL11344012 | 0.94 | THRA (0.55) | LTB4RLTB4R2ALOX5PTGS2THRA | |
| SCHEMBL16933732 | 0.94 | LTB4R (0.53) | LTB4RLTB4R2ALOX5PTGS2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999065309-A1 | METHODS FOR INCREASING LEVELS OF ACETYLCHOLINE | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |