SCHEMBL8523288

SCHEMBL8523288

C#COc1ccc(Br)c(Br)c1Br

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11343888 0.81 TDP1 (0.37) TDP1
SCHEMBL11343891 0.81 TDP1 (0.37) TDP1
SCHEMBL9501918 0.80
SCHEMBL4190024 0.72 TDP1 (0.55) TDP1
SCHEMBL29492146 0.72 TDP1 (0.55) TDP1
SCHEMBL10895169 0.71
SCHEMBL7553909 0.71 MAPK1 (0.58) TDP1
SCHEMBL27941909 0.70 TDP1 (0.40) TDP1
SCHEMBL7558433 0.70 HTR7 (0.38)
SCHEMBL465076 0.69 MAPT (0.46) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807015-B1 PREVENTION OF GROOVE TIP DEFORMATION IN BRIGHTNESS ENHANCEMENT FILM MINNESOTA MINING & MFG (US) 1999-08-25 EP claimed
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP claimed