Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042015 | 0.75 | FAAH (0.45) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL17069014 | 0.74 | CCNB2 (0.51) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL28063931 | 0.73 | HSD17B10 (0.54) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL17283595 | 0.72 | SCN2A (0.59) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL31147801 | 0.67 | TAAR1 (0.60) | IDO1ALDH1A1MAPTHPGDMPO | |
| SCHEMBL7636733 | 0.67 | TAAR1 (0.60) | IDO1ALDH1A1MAPTHPGDMPO | |
| SCHEMBL28309152 | 0.65 | ALDH1A1 (0.53) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL20348822 | 0.65 | PDE4D (0.45) | IDO1KDM4EALDH1A1MAPTHPGD | |
| 1-Isopentoxy-2-Methoxybenzene SCHEMBL791645 | 0.63 | HTT (0.60) | IDO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8523321 | 0.63 | IDO1 (0.44) | IDO1GSK3BKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904274-A4 | FARNESYL TRANSFERASE INHIBITORS | BIOMEASURE INC (US) | 1999-12-29 | — | — | EP | claimed |
| EP-0904274-A1 | FARNESYL TRANSFERASE INHIBITORS | Biomeasure Incorporated (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997030053-A1 | FARNESYL TRANSFERASE INHIBITORS | BIOMEASURE INCORPORATED (US) | 1997-08-21 | — | — | WO | claimed |