⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789580 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL641747 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL490330 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL28823321 | 0.75 | — | — | |
| SCHEMBL10617925 | 0.74 | — | — | |
| Furfural SCHEMBL28220975 | 0.74 | — | — | |
| Furfural SCHEMBL7797598 | 0.74 | — | — | |
| SCHEMBL37113 | 0.72 | — | — | |
| SCHEMBL14315272 | 0.72 | — | — | |
| SCHEMBL2830604 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | claimed |
| US-9675694-B2 | Polycyclic agents for the treatment of respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2017-06-13 | — | — | US | claimed |
| US-20140004111-A1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-01-02 | — | — | US | claimed |
| US-8598194-B2 | Polycyclic agents for the treatment of respiratory syncytial virus infections | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2013-12-03 | — | — | US | claimed |
| CN-102379872-A | Compounds, compositions and methods of inhibiting a-synuclein toxicity | WHITEHEAD BIOMEDICAL INST | 2012-03-21 | — | — | CN | claimed |
| EP-2069353-B1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENT MANAGEMENT (AU) | 2011-11-09 | — | — | EP | claimed |
| EP-1802303-B1 | COMPOUNDS, COMPOSITIONS AND METHODS OF INHIBITING A-SYNUCLEIN TOXICITY | WHITEHEAD BIOMEDICAL INST (US) | 2011-11-02 | — | — | EP | claimed |
| US-20100021458-A1 | POLYCYCLIC AGENTS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS INFECTIONS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2010-01-28 | — | — | US | claimed |
| CN-101410384-A | Compounds and methods for modulating protein trafficking | FOLDRX PHARMACEUTICALS INC (US) | 2009-04-15 | — | — | CN | claimed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| WO-1997030995-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-28 | — | — | WO | claimed |
| US-5599820-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-02-04 | — | — | US | claimed |
| EP-0690856-A4 | — | UNIV NEW YORK (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0690856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-01-10 | — | — | EP | claimed |
| US-5475011-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-12-12 | — | — | US | claimed |
| WO-1994022856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1994-10-13 | — | — | WO | claimed |
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |
| EP-0372470-A2 | Novel alpha-cyano-beta-oxopropionamides | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | claimed |
| US-4831152-A | INTERMEDIATES FOR REDUCING AGENTS, ANTIOXIDANTS AND CYAN-IMAGE FORMING COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| US-4276417-A | TREATMENT OF VASCULAR-CONDITION HYPERTENSION | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | claimed |