Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523480 | 1.00 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL815076 | 0.88 | NOS1 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL432351 | 0.88 | — | — | |
| SCHEMBL15536154 | 0.85 | — | — | |
| SCHEMBL10888358 | 0.80 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL10888364 | 0.80 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL10221 | 0.78 | — | — | |
| SCHEMBL10355207 | 0.78 | — | — | |
| SCHEMBL820708 | 0.78 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL18636753 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013478-A | Electromagnetic radiation resistance; miscibility; dielectrics; rotation and guest/host cells | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | claimed |
| EP-0110205-B1 | COLOURED LIQUID CRYSTAL MIXTURES CONTAINING PHENYL ETHANES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-12-09 | — | — | EP | claimed |
| US-4676604-A | RADIATION RESISTANCE; MISCIBILITY; ROTATION ELECTROPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-30 | — | — | US | claimed |
| US-4613208-A | ELECTROOPTICS; ULTRAVIOLET RADIATION STABILITY; QUICK RESPONSE | HOFFMANN-LA ROCHE INC. (US) | 1986-09-23 | — | — | US | claimed |
| EP-0107116-B1 | DICYANOBENZENES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-08-27 | — | — | EP | claimed |
| US-4583826-A | Phenylethanes | HOFFMANN-LA ROCHE INC. (US) | 1986-04-22 | — | — | US | claimed |
| US-4565425-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1986-01-21 | — | — | US | claimed |
| EP-0110205-A2 | Coloured liquid crystal mixtures containing phenyl ethanes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-13 | — | — | EP | claimed |
| JP-61221171-A | — | — | None | — | — | JP | disclosed |
| JP-62096469-A | — | — | None | — | — | JP | disclosed |
| JP-62013485-A | — | — | None | — | — | JP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5792386-A | A MIXTURE OF ALKYLCYCLOHEXYL(PHENYLENE)DIFLUROMETHOXY-BENZENES AND FLUORO-CONTAINING COMPOUNDS; LOW VISCOSITY; LOW TEMPERATURE MISCIBILITY; HEAT AND CHEMICAL RESISTANCE; ACTIVE MATRIX | CHISSO CORPORATION (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5728319-A | Liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0122389-A2 | Liquid crystal components having an alkenyl chain | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |
| US-4460770-A | Liquid crystal mixture | HOFFMANN-LA ROCHE INC. (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0111695-A2 | Pyridazine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0110205-A2 | Coloured liquid crystal mixtures containing phenyl ethanes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-13 | — | — | EP | disclosed |
| EP-0110205-A2 | Coloured liquid crystal mixtures containing phenyl ethanes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-13 | — | — | EP | disclosed |
| EP-0107116-A1 | Dicyanobenzenes | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-02 | — | — | EP | disclosed |