Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310728 | 1.00 | GRIN1 (0.36) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 | |
| SCHEMBL21225273 | 0.93 | GRIN1 (0.38) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 | |
| SCHEMBL21225643 | 0.88 | GRIN1 (0.37) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 | |
| SCHEMBL21225471 | 0.88 | GRIN1 (0.40) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 | |
| SCHEMBL9234226 | 0.88 | OPRM1 (0.34) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 | |
| SCHEMBL16751001 | 0.85 | GRIN1 (0.32) | GRIN1GRIN2AGRIN2BOTUD7B | |
| SCHEMBL22834163 | 0.84 | OPRM1 (0.34) | OPRM1OPRL1SLC6A9 | |
| Water SCHEMBL29623096 | 0.83 | OPRM1 (0.33) | OPRM1OPRL1SLC6A9 | |
| SCHEMBL9948790 | 0.83 | HSD17B10 (0.43) | HSD17B10 | |
| SCHEMBL24339081 | 0.81 | GRIN1 (0.30) | GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007413-A1 | SUBSTANCE P INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |