Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234226 | 0.88 | OPRM1 (0.34) | HSD17B10 | |
| SCHEMBL30310728 | 0.83 | GRIN1 (0.36) | HSD17B10 | |
| SCHEMBL8523550 | 0.83 | GRIN1 (0.36) | HSD17B10 | |
| SCHEMBL21225273 | 0.79 | GRIN1 (0.38) | HSD17B10 | |
| SCHEMBL21225643 | 0.78 | GRIN1 (0.37) | — | |
| SCHEMBL21225471 | 0.78 | GRIN1 (0.40) | — | |
| SCHEMBL9948870 | 0.77 | GRIN2B (0.40) | HSD17B10 | |
| SCHEMBL9949023 | 0.74 | OPRL1 (0.58) | HSD17B10CYP2D6 | |
| SCHEMBL19329547 | 0.74 | HSD17B10 (0.44) | HSD17B10CYP2D6 | |
| SCHEMBL1632308 | 0.73 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165331-A1 | Di/tri-aza-spiro-C9-C11alkanes | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165331-A1 | Di/tri-aza-spiro-C9-C11alkanes | TACR2, TACR1, AGTR1 | HSD17B10 1178/4885CYP1A2 199/4885CYP2D6 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.