Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539226 | 0.80 | MAOB (0.42) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL8191154 | 0.75 | MAOB (0.41) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL1826881 | 0.72 | ALDH1A1 (0.42) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL1826879 | 0.72 | ALDH1A1 (0.42) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL2051056 | 0.71 | MAOB (0.46) | ALDH1A1MAOBMEN1KMT2AHDAC6 | |
| SCHEMBL5845622 | 0.71 | MAOB (0.50) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL14946408 | 0.71 | MAOB (0.50) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL7649592 | 0.71 | MAOB (0.50) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL373962 | 0.71 | MAOB (0.50) | CYP2C19ALDH1A1TSHRMAOBMEN1 | |
| SCHEMBL9650544 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TSHRMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859277-A | Silicon-containing solid support linker | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-01-12 | — | — | US | disclosed |