Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 18/20 | 1.00 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523600 | 1.00 | ADK (1.00) | ADKHASPINSLC29A1DOT1LNPC1 | |
| SCHEMBL26522923 | 0.88 | ADK (1.00) | ADKHASPINSLC29A1DOT1LNPC1 | |
| SCHEMBL8331141 | 0.87 | ADK (1.00) | ADKSLC29A1 | |
| SCHEMBL8331139 | 0.87 | ADK (1.00) | ADKSLC29A1 | |
| SCHEMBL8975530 | 0.87 | ADK (0.78) | ADKDOT1L | |
| Iodotubercidin SCHEMBL16978206 | 0.86 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| SCHEMBL8323713 | 0.86 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL8328935 | 0.86 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| Iodotubercidin SCHEMBL13021361 | 0.86 | ADK (0.83) | ADKHASPINSLC29A1DOT1LNPC1 | |
| SCHEMBL2033304 | 0.86 | ADK (1.00) | ADKHASPINSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684953-A4 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. | GENSIA INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0684953-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018215-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |