Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | DRD2 | P14416 | 8/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 7/20 | 0.65 |
| ▸ | HTR7 | P34969 | 6/20 | 0.65 |
| ▸ | HTR6 | P50406 | 6/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793025 | 0.94 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL7722977 | 0.94 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL791116 | 0.88 | ACHE (0.77) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL1545611 | 0.87 | ACHE (0.93) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL1544617 | 0.87 | ACHE (0.75) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL791471 | 0.87 | ACHE (0.75) | ACHEDRD2SLC6A4HTR2AHTR6 | |
| Propylamine SCHEMBL28972666 | 0.86 | DRD2 (0.91) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL1545291 | 0.86 | ACHE (0.73) | ACHEDRD2SLC6A4HTR2AHTR6 | |
| SCHEMBL8871775 | 0.83 | ACHE (0.77) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL7351612 | 0.83 | ACHE (0.80) | ACHEDRD2SLC6A4HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001834-A | PSYCHOLOGICAL DISORDERS, ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| US-5965546-A | ANTIPSYCHOTIC AND ANALGESIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-12 | — | — | US | disclosed |