Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 6/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720936 | 0.89 | SIRT2 (0.39) | SIGMAR1LMNAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7208229 | 0.88 | SIGMAR1 (0.40) | SIGMAR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8204758 | 0.80 | SIGMAR1 (0.43) | SIGMAR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8519145 | 0.78 | TNNI3K (0.47) | TNNI3KEGFRLMNAPTBP1MEN1 | |
| SCHEMBL6727640 | 0.77 | SIGMAR1 (0.63) | SIGMAR1LMNAMEN1KMT2ATSHR | |
| SCHEMBL6728082 | 0.77 | SIGMAR1 (0.40) | SIGMAR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6724377 | 0.76 | GRIK1 (0.41) | SIGMAR1ATMLMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7204073 | 0.76 | SIGMAR1 (0.64) | SIGMAR1LMNAMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7207132 | 0.76 | SIGMAR1 (0.41) | SIGMAR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6728580 | 0.75 | SIGMAR1 (0.39) | SIGMAR1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | claimed |