Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720790 | 0.88 | SIRT2 (0.43) | LMNASMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL8523992 | 0.78 | TNNI3K (0.38) | TNNI3KLMNAPTBP1EGFRBRAF | |
| SCHEMBL8556316 | 0.78 | POLB (0.51) | TNNI3KLMNAPTBP1MEN1KMT2A | |
| SCHEMBL6720893 | 0.75 | MAPT (0.46) | SMN1; SMN2MEN1KMT2AGAARAB9A | |
| SCHEMBL6728881 | 0.75 | SIGMAR1 (0.48) | SMN1; SMN2GAARAB9AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7202744 | 0.74 | SIGMAR1 (0.50) | SMN1; SMN2GAARAB9AMAPTALDH1A1 | |
| SCHEMBL4151992 | 0.74 | LMNA (0.52) | TNNI3KLMNAPTBP1EGFRSMN1; SMN2 | |
| SCHEMBL6728090 | 0.73 | MEN1 (0.34) | LMNASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6728898 | 0.73 | GRIK1 (0.58) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL264637 | 0.71 | TNNI3K (0.60) | TNNI3KLMNAEGFRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |