Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 6/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPD | P32754 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524457 | 0.76 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8809898 | 0.74 | F2RL3 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL8484212 | 0.73 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2RAB9AALDH1A1ADRA1A | |
| SCHEMBL8595988 | 0.71 | EIF4E (0.35) | SMN1; SMN2RAB9ALMNANPC1THRB | |
| SCHEMBL8811476 | 0.71 | MAPT (0.38) | SMN1; SMN2RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL8810747 | 0.70 | MEN1 (0.32) | SMN1; SMN2LMNA | |
| SCHEMBL8483512 | 0.70 | KDM4E (0.45) | TSHRSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8814897 | 0.70 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8590947 | 0.69 | DHPS (0.37) | SMN1; SMN2LMNATHRB | |
| SCHEMBL8595340 | 0.69 | RORB (0.34) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999018102-A1 | FUNGICIDAL AND ARTHROPODICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |