Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913604 | 0.79 | ALDH1A1 (0.39) | NR1H2NR1H3ALDH1A1TSHR | |
| SCHEMBL8192574 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL27259117 | 0.78 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL31468473 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27258709 | 0.75 | ALDH1A1 (0.35) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL373961 | 0.74 | ALDH1A1 (0.44) | ALDH1A1IDO1TSHR | |
| Hydrochloric Acid SCHEMBL27258912 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL7064746 | 0.74 | ALDH1A1 (0.34) | NR1H2NR1H3ALDH1A1 | |
| SCHEMBL31468469 | 0.72 | ALDH1A1 (0.33) | ALDH1A1TSHRCYP2D6CYP2C19 | |
| SCHEMBL29434682 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859277-A | Silicon-containing solid support linker | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-01-12 | — | — | US | disclosed |