SCHEMBL7064746

SCHEMBL7064746

C=Cc1ccccc1[Si](C)(C)CCCC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8522100 0.93 KCNH2 (0.36) ALDH1A1
SCHEMBL31468453 0.88 HTT (0.35)
SCHEMBL30872686 0.86 ALDH1A1 (0.34) ALDH1A1
SCHEMBL31468579 0.83 SIGMAR1 (0.37) ALDH1A1
SCHEMBL31468636 0.82 HRH1 (0.34) ALDH1A1
SCHEMBL27258709 0.81 ALDH1A1 (0.35) ALDH1A1NR1H2NR1H3
SCHEMBL31468521 0.80 HTT (0.35)
Hydrochloric Acid SCHEMBL27258912 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL10913604 0.78 ALDH1A1 (0.39) ALDH1A1NR1H2NR1H3
SCHEMBL8192574 0.77 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104159927-A Hydrogenated aromatic alkenyl and diene copolymers containing comonomers that have silyl hydride units and functionalized analogues thereof DYNASOL ELASTOMEROS SA 2014-11-19 CN disclosed
EP-1404690-A1 NOVEL MULTINUCLEAR HALF METALLOCENE CATALYST AND PREPARATION OF STYRENE POLYMER USING THE SAME LG Chem, Ltd. (KR) 2004-04-07 EP disclosed
WO-2003006473-A1 NOVEL MULTINUCLEAR HALF METALLOCENE CATALYST AND PREPARATION OF STYRENE POLYMER USING THE SAME LG CHEM, LTD. (KR) 2003-01-23 WO disclosed