Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525270 | 0.82 | SMN1; SMN2 (0.70) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL8484612 | 0.81 | RAB9A (0.47) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL8525368 | 0.80 | SMN1; SMN2 (0.60) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL8480061 | 0.78 | PDE3B (0.68) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL8524263 | 0.76 | RAB9A (0.51) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8480857 | 0.76 | KDM4E (0.50) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL8525211 | 0.76 | CDC25A (0.43) | RAB9AMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8524006 | 0.74 | RAB9A (0.44) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL6651931 | 0.72 | MAPT (0.65) | RAB9AMAPTNPC1MMP12SMN1; SMN2 | |
| SCHEMBL16090353 | 0.71 | MEN1 (0.59) | RAB9AMAPTNPC1MMP12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |