Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525270 | 0.93 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL8480061 | 0.87 | PDE3B (0.68) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL18122053 | 0.83 | MAPT (0.85) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL8523935 | 0.82 | NPC1 (0.44) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL8524263 | 0.82 | RAB9A (0.51) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL8524059 | 0.80 | RAB9A (0.49) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL6197654 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL6651931 | 0.79 | MAPT (0.65) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8480857 | 0.79 | KDM4E (0.50) | SMN1; SMN2MAPTPOLBALDH1A1HTT | |
| SCHEMBL6201294 | 0.79 | MAPT (0.66) | SMN1; SMN2MAPTPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |