Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4462545 | 0.65 | — | — | |
| SCHEMBL19266253 | 0.62 | — | — | |
| SCHEMBL3408186 | 0.59 | TSHR (0.30) | — | |
| SCHEMBL18994815 | 0.58 | — | — | |
| Water SCHEMBL27888237 | 0.55 | — | — | |
| SCHEMBL18792957 | 0.55 | — | — | |
| SCHEMBL21126011 | 0.53 | — | — | |
| SCHEMBL24486015 | 0.47 | — | — | |
| SCHEMBL20972620 | 0.47 | ALDH1A1 (0.31) | — | |
| SCHEMBL22958063 | 0.47 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910591-A1 | SYNDIOTACTIC/ATACTIC BLOCK POLYOLEFINS, CATALYSTS AND PROCESSES FOR PRODUCING THE SAME | FINA RESEARCH S.A. (BE) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998002469-A1 | SYNDIOTACTIC/ATACTIC BLOCK POLYOLEFINS, CATALYSTS AND PROCESSES FOR PRODUCING THE SAME | FINA RESEARCH S.A. (BE) | 1998-01-22 | — | — | WO | disclosed |