Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466875 | 0.76 | HRH4 (0.57) | CLK1DYRK1AHRH4ROCK1PDE3B | |
| SCHEMBL22607307 | 0.75 | HRH4 (0.42) | CLK1DYRK1AHRH4PDE3BPDE3A | |
| SCHEMBL1812266 | 0.70 | HRH4 (0.58) | CLK1DYRK1AHRH4ROCK1PDE3B | |
| SCHEMBL17324741 | 0.69 | HRH4 (0.61) | CLK1DYRK1AHRH4ROCK1PDE3B | |
| SCHEMBL8524119 | 0.69 | HRH4 (0.50) | CLK1DYRK1AHRH4ROCK1PDE3B | |
| SCHEMBL30980411 | 0.69 | CYP1A2 (0.61) | CLK1DYRK1AHRH4ROCK1ADORA3 | |
| SCHEMBL5275762 | 0.69 | HRH4 (0.42) | CLK1DYRK1AHRH4ROCK1PDE3B | |
| SCHEMBL31295445 | 0.67 | HRH4 (0.51) | CLK1DYRK1AHRH4ROCK1DRD2 | |
| SCHEMBL30173383 | 0.66 | CLK1 (0.61) | CLK1DYRK1AHRH4ROCK1PDE3B | |
| SCHEMBL17321412 | 0.66 | HRH4 (0.57) | CLK1DYRK1AHRH4ROCK1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |