Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FSHR | P23945 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7869769 | 0.99 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2NAMPTKMT2A | |
| SCHEMBL7868103 | 0.87 | ADRA2A (0.45) | KMT2AMEN1HTTADRA2AADORA3 | |
| SCHEMBL7869019 | 0.85 | ADRA2A (0.44) | ALDH1A1NAMPTKMT2AMEN1HPGD | |
| SCHEMBL7869770 | 0.85 | ADRA2A (0.46) | TSHRSMN1; SMN2HTTADRA2AADORA3 | |
| SCHEMBL7869024 | 0.84 | ALDH1A1 (0.56) | TSHRALDH1A1SMN1; SMN2NAMPT | |
| SCHEMBL7866501 | 0.83 | KCNH2 (0.45) | ALDH1A1SMN1; SMN2NAMPTKMT2AMEN1 | |
| SCHEMBL8491686 | 0.83 | ADRA2A (0.46) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL7873013 | 0.82 | PRMT5 (0.47) | ALDH1A1SMN1; SMN2NAMPTKMT2AMEN1 | |
| SCHEMBL7866488 | 0.82 | ADRA2A (0.49) | TSHRALDH1A1SMN1; SMN2ADRA2AADORA3 | |
| Hydrochloric Acid SCHEMBL7861439 | 0.82 | ADRA2A (0.44) | NAMPTHTTADRA2AADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |