Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 2/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998665 | 0.81 | GSK3B (0.48) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL8525618 | 0.78 | EGFR (0.38) | CASP7GAAMAPTALDH1A1HTT | |
| SCHEMBL3144271 | 0.77 | GAA (0.45) | GAAMAPTALDH1A1HTTHPGD | |
| SCHEMBL11251701 | 0.76 | GSK3B (0.42) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL11251693 | 0.76 | GSK3B (0.42) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL27047100 | 0.75 | GSK3B (0.61) | GSK3BCASP3CASP7CASP6CASP8 | |
| SCHEMBL17951849 | 0.74 | GAA (0.43) | GAAMAPTALDH1A1HTTHPGD | |
| SCHEMBL24990048 | 0.74 | IDO1 (0.46) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL8983753 | 0.73 | GSK3B (0.94) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL27572997 | 0.73 | GSK3B (0.94) | GSK3BCASP3CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962658-A | (3-oxoisoindolin-1-ylidine)propandinitrile derivatives and method for preparing the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 1999-10-05 | — | — | US | claimed |
| US-5962658-A | (3-oxoisoindolin-1-ylidine)propandinitrile derivatives and method for preparing the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 1999-10-05 | — | — | US | disclosed |
| US-5962658-A | (3-oxoisoindolin-1-ylidine)propandinitrile derivatives and method for preparing the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 1999-10-05 | — | — | US | disclosed |
| US-5962658-A | (3-oxoisoindolin-1-ylidine)propandinitrile derivatives and method for preparing the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 1999-10-05 | — | — | US | disclosed |
| CN-1215049-A | (3-oxioisoindolin-1-ylidine) propandinitrile derivatives and method for preparing the same | SAMSUNG ELECTRONICS CO LTD (KR) | 1999-04-28 | — | — | CN | disclosed |