Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524149 | 0.78 | GSK3B (0.52) | EGFRALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL8525627 | 0.76 | TDP1 (0.62) | EGFRALDH1A1SMN1; SMN2CYP3A4MAPK1 | |
| SCHEMBL372282 | 0.74 | ATM (0.58) | ATMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14890696 | 0.73 | ATM (0.56) | ATMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12114273 | 0.70 | ALDH1A1 (0.53) | EGFRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11034115 | 0.70 | ALDH1A1 (0.56) | EGFRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Alcohol SCHEMBL11504572 | 0.69 | ATM (0.49) | ATMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12857784 | 0.66 | NPC1 (0.55) | ATMALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7044925 | 0.66 | EGFR (0.38) | EGFRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9037526 | 0.65 | RET (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962658-A | (3-oxoisoindolin-1-ylidine)propandinitrile derivatives and method for preparing the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 1999-10-05 | — | — | US | disclosed |