Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524219 | 0.80 | ACP1 (0.34) | MTNR1AMTNR1B | |
| SCHEMBL8524763 | 0.72 | NPY1R (0.37) | NPY1RHTR2AHTR2CDRD2SLC6A3 | |
| SCHEMBL3244758 | 0.67 | MTNR1A (0.57) | HTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL3253551 | 0.66 | MTNR1A (0.56) | NPY1RHTR2AHTR2CDRD2MTNR1A | |
| SCHEMBL8524221 | 0.66 | TAAR1 (0.31) | SLC6A3 | |
| SCHEMBL3248497 | 0.61 | MTNR1A (0.59) | MTNR1AMTNR1B | |
| SCHEMBL11161666 | 0.58 | NPY1R (0.41) | NPY1RHTR2AHTR2CDRD2SLC6A3 | |
| SCHEMBL11171282 | 0.58 | HRH3 (0.44) | NPY1RHTR2AHTR2CDRD2SLC6A3 | |
| SCHEMBL1537773 | 0.57 | GPR3 (0.46) | — | |
| SCHEMBL11166862 | 0.57 | HRH3 (0.46) | NPY1RHTR2AHTR2CDRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856510-A | SELECTIVE FOR 5-HT(1D)-LIKE RECEPTORS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-01-05 | — | — | US | disclosed |