Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351054 | 0.86 | SMN1; SMN2 (0.50) | HPGDKDM4EKMT2AGAAHSD17B10 | |
| SCHEMBL8322740 | 0.84 | MAPT (0.48) | HPGDKDM4EKMT2AGAAHSD17B10 | |
| SCHEMBL8664998 | 0.81 | TDP1 (0.56) | HPGDKMT2AGAALMNAPOLB | |
| SCHEMBL4856473 | 0.80 | EPHX2 (0.54) | HPGDKDM4EKMT2AIDH1GAA | |
| SCHEMBL4851692 | 0.79 | S1PR1 (0.45) | HPGDKDM4EKMT2AIDH1LMNA | |
| SCHEMBL7475639 | 0.78 | SMN1; SMN2 (0.56) | KMT2AIDH1GAAHSD17B10LMNA | |
| SCHEMBL24726246 | 0.77 | LMNA (0.44) | LMNAPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL16571563 | 0.77 | KDM4E (0.51) | HPGDKDM4EKMT2AIDH1GAA | |
| SCHEMBL8575846 | 0.76 | SMN1; SMN2 (0.46) | KDM4EKMT2AHSD17B10LMNAPOLB | |
| SCHEMBL16571344 | 0.76 | GAA (0.50) | HPGDKDM4EKMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |