Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463419 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2PPARGPPARAPOLBKMT2A | |
| SCHEMBL6548321 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL9616847 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL23754109 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL29936845 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL8524271 | 0.76 | HPGD (0.46) | SMN1; SMN2LMNAPOLBHSD17B10PDE3B | |
| SCHEMBL3829814 | 0.75 | LMNA (0.50) | SMN1; SMN2LMNAPOLBRXFP1PDE3B | |
| Hydrochloric Acid SCHEMBL6547942 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL4439565 | 0.75 | RXFP1 (0.54) | SMN1; SMN2LMNAPOLBRXFP1TSHR | |
| SCHEMBL8772025 | 0.75 | LMNA (0.52) | SMN1; SMN2LMNAPOLBRXFP1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |