Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524581 | 0.77 | MCL1 (0.34) | — | |
| SCHEMBL8649192 | 0.75 | PDCD1LG2 (0.41) | — | |
| SCHEMBL7466400 | 0.72 | HTT (0.35) | — | |
| SCHEMBL7473579 | 0.70 | GLP1R (0.35) | HRH4 | |
| SCHEMBL7471934 | 0.69 | GRIN1 (0.50) | HRH4 | |
| SCHEMBL8490077 | 0.68 | GLP1R (0.31) | — | |
| SCHEMBL7470542 | 0.68 | GRIN1 (0.39) | HRH4 | |
| SCHEMBL8650855 | 0.66 | GRIN1 (0.42) | HRH4 | |
| SCHEMBL7476576 | 0.66 | GRIN1 (0.35) | HRH4 | |
| SCHEMBL8649190 | 0.66 | GRIN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863917-A | ANXIOLYTIC AGENT, ANTICONVULSANTS, ANALGESICS AND NEUROPROTECTIVES. | PFIZER, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |